Xi'an Le-Nutra Ingredients Inc is one of the most professional manufacturers and suppliers of celery extract apigenin in China, featured by quality products and low price. Please rest assured to wholesale bulk celery extract apigenin for sale here from our factory. Customized orders are welcome.
Apigenin Flavonoid Manufacturer
Our Celery Extract Apigenin starts from sourcing the best quality Celery plant. And slecting the seed, then the celery seeds are screened, crushed, and placed in an alcohol container, stirred, and then left to stand; the powdered celery seeds are fused with the alcohol to change from powder to granular; the granular mixture in the container is extracted in three times; the extracted granular material is filtered through the solution and processed by depressurisation and concentration so as to make the powdered apigenin. The extraction ratio of celery seed to apigenin is 150:1. the purity of our apigenin in each batch is over 98%. Every batch of our Apigenin is above 98.0% purity, Consistent quality and sustainable development have always been our production philosophy.

Why Choose Us
1. With over 10 years of experience in research and production in the industry, our excellent technical team with professional skills to ensure that we meet the different needs of customers for content.
2. A professional service team will solve customer problems timely and supply reasonable solutions according to each customer's needs.
3. Our primary focus extends across the European and American regions, a testament not only to our commitment to product excellence but also to our recognized leadership within the field.
4. Safe and reliable logistics and distribution, we provide flexible delivery times and quickly respond to customers' different needs for transportation services.
Product Description
Pure Apigenin powder is a natural flavonoid derived from the celery plant (Apium graveolens). Known for its potent antioxidant and anti-inflammatory properties, apigenin has garnered interest for its potential health benefits, including its ability to modulate immune responses, and protect against neurodegenerative diseases. Found abundantly in celery and other vegetables like parsley and chamomile, apigenin can be consumed through diet or supplements. Its therapeutic properties are being explored in various scientific studies, highlighting its promise as a natural compound with significant health-promoting effects.
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Item |
Standard |
Test Result |
Test Method |
| Apigenin | Above 98.0% | 98.4% | HPLC |
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Physical Data |
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Appearance |
Yellow-green |
Conform |
Organoleptic |
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Odor&Taste |
Characteristic |
Conform |
Organoleptic |
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Analytical Quality |
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Identification |
Identical to R.S.Sample |
Conform |
HPTLC |
|
Sieve analysis |
100% through 80 mesh |
Conform |
USP34 |
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Loss on drying |
≤5.0% |
Eur.Ph.6.0 |
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|
Ash |
≤10.0% |
Eur.Ph7.0 |
|
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Bulk density |
40~60g/100mL |
g/100mL |
Eur.Ph.7.0 |
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Heavy Metal |
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Pb |
≤3ppm |
Conform |
Eur.Ph.7.0 |
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As |
≤2ppm |
Conform |
Eur.Ph.7.0 |
|
Cd |
≤1ppm |
Conform |
Eur.Ph.7.0 |
|
Hg |
≤0.1ppm |
Conform |
Eur.Ph.7.0 |
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Microbiological Test |
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Total Plate Count |
≤10,000cfu/g |
Conform |
USP34 |
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Yeast&Mold |
≤1000cfu/g |
Conform |
USP34 |
|
E.Coli |
Negative |
Negative |
USP34 |
|
Salmonella |
Negative |
Negative |
USP34 |
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Conclusion:Conform with specification, Non-GMO, Non-irradiation, Allergen, TSE/BSE Free. |
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Storage:Store in cool and dry places. Keep away from strong light and heat. |
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Packing:By 25kgs/Drum, inner by plastic bag or aluminum foil bag. |
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Shelf Life:24 months under the above condition, and in it's original package. |
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Product Function
1. Antioxidant Activity: Apigenin helps neutralize free radicals, mitigating oxidative stress and preventing cellular damage, which can lead to chronic diseases.
2. Anti-inflammatory Effects: Celery Extract Apigenin inhibits the production of inflammatory cytokines and enzymes, significantly reducing inflammation and alleviating related disorders.
3. Neuroprotective Properties: Apigenin supports brain health by protecting neurons from damage, reducing neuroinflammation, and enhancing cognitive functions such as memory and learning. This makes it a potential therapeutic agent for neurodegenerative diseases like Alzheimer's and Parkinson's.
4. Cardiovascular Health: By reducing oxidative stress and inflammation, apigenin contributes to cardiovascular health. It helps lower blood pressure, improves lipid profiles, and plays a role in preventing heart disease.
5. Antimicrobial Activity: Apigenin exhibits antimicrobial properties against various bacteria, viruses, and fungi, making it beneficial in fighting infections.
6. Hormonal Balance: It has phytoestrogenic properties, which allow it to mimic estrogen in the body, aiding in hormonal balance and potentially alleviating menopausal symptoms.
7. Anti-anxiety and Sedative Effects: Apigenin binds to benzodiazepine receptors in the brain, producing calming effects and reducing anxiety, making it a natural alternative for managing anxiety and promoting relaxation.
How does Apigenin Improve Anxiety?
Interaction with GABA Receptors
Apigenin binds to benzodiazepine receptors, enhancing GABA activity and producing a calming effect similar to anti-anxiety medications.
Reduction of Neuroinflammation
It reduces neuroinflammation by decreasing pro-inflammatory cytokines and inhibiting inflammatory pathways, stabilizing mental state.
Modulation of Neurotransmitter Levels
Apigenin influences serotonin and dopamine levels, helping to alleviate anxiety and improve mood.
Oxidative Stress Reduction
Its antioxidant properties reduce oxidative stress, protecting neurons and supporting better mental health.
Regulation of the HPA Axis
Apigenin helps regulate the stress response of the HPA axis, reducing anxiety levels.
Enhancement of Neurogenesis
It promotes the formation of new neurons in the hippocampus, aiding in mood regulation and reducing anxiety.
Application
1. Inhibit bacteria
Medical research has found that flavonoids in pure apigenin can regulate the fragility and permeability of capillaries, scavenge free radicals, and inhibit bacteria. Among them, coumarin is a class of phenylpropyl compounds with anti-inflammatory, antispasmodic, sedative, antibacterial and other effects; furocoumarins have photosensitivity and antibacterial effects on the skin; chlorophyll has important anti-inflammatory and antibacterial effects. Promotes wound healing.

2. Hypotensive
Derivatives of coumarin and furanocoumarin in celery root powder have antihypertensive, lipid-lowering and cholesterol-lowering effects.
3. Lower blood lipids
Bulk celery powder was able to lower blood lipids. Thirteen fatty acids were detected in celery seed oil, of which unsaturated fatty acids accounted for 69.20%. Among the 6 kinds of unsaturated fatty acids detected, 6-octadecenoic acid was the highest in content, with a content of 58.18%; the content of linoleic acid was as high as 9.21%. Therefore, it has very important physiological functions and activities, which can lower blood lipids and prevent arteriosclerosis. If the human body is deficient, there will be adverse reactions such as growth retardation, skin lesions, and liver degeneration.
4. Calm down
Butylphthalide in Celery Extract Apigenin is a class of compounds with sedative properties. At present, 5 kinds of such components have been extracted from celery seed oil, among which 3-n-butyl-phthaloyl lactone and celery sedative are relatively high in celery, so celery on dinner has Very good sleep aid.
Latest News
Le-Nutra Ingredients, one of the leading Manufacturers in the global ingredients industry(used for Dietary Supplement, Cosmetics, Personal Care Products), has recently took it's first Assessment at EcoVadis and gained a Bronze Medal.
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