Decapeptide-4 Powder

Xi'an Le-Nutra Ingredients Inc is one of the most professional manufacturers and suppliers of decapeptide-4 powder in China, featured by quality products and low price. Please rest assured to wholesale bulk decapeptide-4 powder for sale here from our factory. Customized orders are welcome.

Decapeptide-4 is a synthetic peptide composed of ten amino acids, including arginine, aspartic acid, cysteine, glutamic acid, leucine, methionine, and tyrosine . It functions as a signaling peptide in cosmetic formulations, mimicking the body's natural repair mechanisms to support collagen and elastin synthesis.

The peptide works through multiple pathways. Research indicates it can penetrate the dermis and stimulate collagen, elastic fiber, and hyaluronic acid production, improving skin water content and reducing fine lines . It also upregulates cytokeratin-15 (CK15), a marker for hair follicle stem cells, and activates the Wnt/β-catenin pathway to support hair follicle activity.

Our Decapeptide-4 Powder is a white to off-white lyophilized powder with high HPLC purity. It dissolves in water and suits serum, cream, and hair care formulations. The recommended use level in cosmetics ranges from 0.005% to 0.1%.

What I find notable about this peptide is the breadth of its positioning. It is not just an anti-wrinkle ingredient. The same molecule shows activity in skin firmness, barrier repair, and hair follicle support . For formulators building multi-functional anti-aging or scalp care lines, that versatility has practical value.

This Decapeptide-4 Powder is supplied for cosmetic manufacturing and formulation development.

We supply Decapeptide-4 Powder with a focus on sequence identity and batch consistency. The peptide is a ten-amino-acid chain, and synthesis byproducts can affect both purity and performance. Our material is tested by HPLC to confirm ≥98% purity, with identity confirmed by mass spectrometry.

Every batch ships with a Certificate of Analysis covering purity, water content, acetate content, and mass spec identity. We report the actual values, not just pass/fail results. The powder is packaged and stored under conditions that protect it from moisture and degradation.

I have seen peptide powders that pass a generic purity spec but fail sequence confirmation. For a cosmetic peptide with a specific mechanism, identity is not optional. It is the difference between the intended active and a related impurity. Our COA includes the mass spec result. When a customer tells me their serum or hair serum performed as expected in stability testing, that is the confirmation that the material was right.

• Collagen and Elastin Synthesis

Decapeptide-4 Powder acts as a signaling peptide that promotes collagen and elastin production. In vitro data shows dose-dependent upregulation of elastin gene expression in human dermal fibroblasts, reaching 2.2-fold at 0.1% concentration . This supports skin firmness and structural integrity.

• Skin Hydration and Barrier Support

The peptide increases hyaluronic acid synthesis and improves skin water content and water-locking ability . It also enhances barrier repair capacity by supporting keratinocyte proliferation.

• Hair Follicle Activation

Research shows Decapeptide-4 Powder upregulates CK15 expression and activates the Wnt/β-catenin pathway, extending the hair follicle anagen phase. In a clinical trial, a 2% hair serum formulation increased hair density by 19% after three months.

• Anti-Wrinkle and Firming

Supplier data indicates the peptide can reduce fine lines, eye wrinkles, and forehead wrinkles caused by muscle contraction . It works by reconstructing skin structure from inside to outside.

Anti-Aging Serums and Creams
Decapeptide-4 Powder suits concentrated serums and creams targeting fine lines, firmness, and skin texture. The low use level makes it practical for premium formulations.

Eye Contour Products
The peptide is effective for eye creams and gels addressing crow's feet and under-eye wrinkles.

Hair Care and Scalp Serums
Decapeptide-4 Powder can be incorporated into hair serums and scalp treatments at 1% to 2% concentration. It pairs well with caffeine or minoxidil in hair growth formulations.

Masks and Hydrogels
The water solubility and low use level make it suitable for sheet mask essences and hydrogel patches for intensive treatments.

Q: What is the recommended use level for Decapeptide-4 Powder?
A: Cosmetic use levels range from 0.005% to 0.1% . For hair care applications, supplier data suggests 1% to 2% . Contact us for formulation-specific guidance.

Q: How should I store the powder?
A: Store at 2–8°C, protected from light and moisture. The lyophilized powder is stable under these conditions for 24 months.

Q: What is the mechanism of action?
A: Decapeptide-4 Powder acts as a signaling peptide, promoting collagen and elastin synthesis. It also upregulates CK15 and activates Wnt/β-catenin signaling to support hair follicle activity.

Q: Is there independent research on this peptide?
A: Independent research is limited. Paula's Choice notes that while there isn't enough independent research to definitively evaluate efficacy, peptides of this nature are generally proven to offer skin restorative benefits . Supplier and patent data support the claimed mechanisms.

Q: Can it be used in hair care products?
A: Yes. Research shows Decapeptide-4 supports hair follicle activity. However, note that claims around hair growth have not been proven in large-scale independent clinical trials.

Q: Can you provide samples?
A: Yes. We send small quantities with a Certificate of Analysis for qualified customers. Contact us with your requirements.

To explore how our Hydrolysed Rice Peptide can enhance your products, contact us at info@lenutra.com, aimee@lenutra.com